Product Datasheet  
REC8 Antibody  
Catalog Number: 34779  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: O95072
    NCBI Gene ID: 9985
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human REC8.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • Meiotic recombination protein REC8 homolog; Cohesin Rec8p; REC8; REC8L1;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total REC8 protein.
  • Applications：  
  • WB
  • Background：  
  • Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II By similarity.

    Parisi S., Mol. Cell. Biol. 19:3515-3528(1999).
    Ota T., Nat. Genet. 36:40-45(2004).
    Ebert L., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.



 
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