Product Datasheet
MRC1 Antibody
Catalog Number: 34773
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P22897
NCBI Gene ID: 4360
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human MRC1.
- other_names:
- Macrophage mannose receptor 1; MMR; CD206 antigen;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total MRC1 protein.
- Background:
Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens.
Taylor M.E., J. Biol. Chem. 265:12156-12162(1990).
Ezekowitz R.A., J. Exp. Med. 172:1785-1794(1990).
Kim S.J., Genomics 14:721-727(1992).
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