Product Datasheet
GLRB Antibody
Catalog Number: 34705
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P48167
NCBI Gene ID: 2743
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human GLRB.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Glycine receptor subunit beta; Glycine receptor 58 kDa subunit;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total GLRB protein.
- Background:
- The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).
Handford C.A., Brain Res. Mol. Brain Res. 35:211-219(1996).
Milani N., Genomics 50:341-345(1998).
Ota T., Nat. Genet. 36:40-45(2004).
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