Product Datasheet  
GGH Antibody  
Catalog Number: 34695  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q92820
    NCBI Gene ID: 8836
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human GGH.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • conjugase; EC 3.4.19.9; folylpolygammaglutamyl hydrolase; gamma-Glu-X carboxypeptidase; gamma-glutamyl hydrolase
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total GGH protein.
  • Applications：  
  • WB
  • Background：  
  • Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates.

    Yao R., Proc. Natl. Acad. Sci. U.S.A. 93:10134-10138(1996).
    Yin D., Gene 238:463-470(1999).
    Basrur V., J. Proteome Res. 2:69-79(2003).



 
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