Product Datasheet  
EIF3K Antibody  
Catalog Number: 34680  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q9UBQ5
    NCBI Gene ID: 27335
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human EIF3K.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • Eukaryotic translation initiation factor 3 subunit K£¬Eukaryotic translation initiation factor 3 subunit 12; eIF-3 p25; eIF-3 p28; eIF3k; Muscle-specific gene M9 protein
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total EIF3K protein.
  • Applications：  
  • WB
  • Background：  
  • Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. HAMAP-Rule MF_03010

    Mayeur G.L., Eur. J. Biochem. 270:4133-4139(2003).
    Nawa G., Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.
    Ye M., Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases.



 
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