Product Datasheet
ELOVL1 Antibody
Catalog Number: 34670
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9BW60
NCBI Gene ID: 64834
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human ELOVL1.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Elongation of very long chain fatty acids protein 1; ELOVL1; SSC1; CGI-88;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total ELOVL1 protein.
- Background:
- Condensing enzyme that catalyzes the synthesis of both saturated and monounsaturated very long chain fatty acids (VLCFAs). Exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.
Asadi A., Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
Lai C.-H., Genome Res. 10:703-713(2000).
Ota T., Nat. Genet. 36:40-45(2004).
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