Product Datasheet  
RNF138 Antibody  
Catalog Number: 34663  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q8WVD3
    NCBI Gene ID: 51444
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human RNF138.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • E3 ubiquitin-protein ligase RNF138; EC 6.3.2.-; RING finger protein 138; Nemo-like kinase-associated RING finger protein; NLK-associated RING finger protein
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total RNF138 protein.
  • Applications：  
  • WB
  • Background：  
  • E3 ubiquitin-protein ligase. Together with NLK, involved in the ubiquitination and degradation of TCF/LEF. Also exhibits auto-ubiquitination activity in combination with UBE2K. May act as a negative regulator in the Wnt/beta-catenin-mediated signaling pathway.

    Wang L., Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
    Ota T., Nat. Genet. 36:40-45(2004).
    Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.



 
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