Product Datasheet
CNTN6 Antibody
Catalog Number: 34620
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9UQ52
NCBI Gene ID: 27255
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human CNTN6.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- contactin 6; contactin-6; NB3; neural adhesion molecule; neural recognition molecule NB-3
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total CNTN6 protein.
- Background:
- Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination By similarity.
Kamei Y., J. Neurosci. Res. 51:275-283(1998).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Mayya V., Sci. Signal. 2:RA46-RA46(2009).
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