Product Datasheet
CFI Antibody
Catalog Number: 34614
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P05156
NCBI Gene ID: 3426
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human CFI.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- C3b-INA; C3B/C4B inactivator; CFAI; complement factor I; factor I
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total CFI protein.
- Background:
- Responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively.
Wilson R.K., Nature 434:724-731(2005).
Goldberger G., Gene 208:17-24(1998).
Wang L., Zou H., J. Proteome Res. 8:651-661(2009).
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