Product Datasheet
CLCNKA Antibody
Catalog Number: 34581
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P51800
NCBI Gene ID: 1187
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from C-terminal of human CLCNKA.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Chloride channel protein ClC-Ka; Chloride channel Ka; ClC-K1;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total CLCNKA protein.
- Background:
- Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. May be important in urinary concentrating mechanisms.
Kieferle S., Proc. Natl. Acad. Sci. U.S.A. 91:6943-6947(1994).
Gregory S.G., Nature 441:315-321(2006).
Estevez R., Nature 414:558-561(2001).
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