Product Datasheet
BORG1 Antibody
Catalog Number: 34556
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: O14613
NCBI Gene ID: 10435
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human BORG1.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Cdc42 effector protein 2; Binder of Rho GTPases 1;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total BORG1 protein.
- Background:
- Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner.
Guru S.C., Genome Res. 7:725-735(1997).
Joberty G., Mol. Cell. Biol. 19:6585-6597(1999).
Hirsch D.S., J. Biol. Chem. 276:875-883(2001)
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