Product Datasheet
PNPLA6 Antibody
Catalog Number: 34862
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q8IY17
NCBI Gene ID: 10908
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human PNPLA6.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Neuropathy target esterase; Patatin-like phospholipase domain-containing protein 6;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total PNPLA6 protein.
- Background:
- Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy.
Lucas S.M., Nature 428:529-535(2004).
Venter J.C., Submitted (SEP-2005).
Korner R., Anal. Chem. 80:9526-9533(2008).
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