Product Datasheet
KIF4A Antibody
Catalog Number: 34591
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: O95239
NCBI Gene ID: 24137
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human KIF4A.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- chromokinesin; chromosome-associated kinesin KIF4A; KIF4; KIF4-G1; kinesin family member 4
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total KIF4A protein.
- Background:
- Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization.
Villard L., Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases.
Oh S.J., Biochim. Biophys. Acta 1493:219-224(2000).
Rentsch A., Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
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