Product Datasheet
RPL27A Antibody
Catalog Number: 34351
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P46776
NCBI Gene ID: 6157
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from C-terminal of human RPL27A.
- appl_detail:
- Western blotting: 1:500~1:3000
Immunofluorescence: 1:100~1:500
- other_names:
- MGC87238; RL27A;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total RPL27A protein.
- Background:
- Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L15P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, multiple processed pseudogenes derived from this gene are dispersed through the genome.
Frigerio J.-M., Biochim. Biophys. Acta 1262:64-68(1995).
Kusuda J., Cytogenet. Cell Genet. 85:248-251(1999).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
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