Product Datasheet
MRPL18 Antibody
Catalog Number: 34321
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9H0U6
NCBI Gene ID: 29074
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human MRPL18.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- 39S ribosomal protein L18; mitochondrial; L18mt; mitochondrial ribosomal protein L18; MRP-L18
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total MRPL18 protein.
- Background:
- Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA.
Wiemann S., Genome Res. 11:422-435(2001).
Zhang Q.-H., Genome Res. 10:1546-1560(2000).The MGC Project Team; Genome Res. 14:2121-2127(2004).
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