Product Datasheet  
PSMD11 Antibody  
Catalog Number: 34307  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: O00231
    NCBI Gene ID: 5717
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human PSMD11.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • 26S proteasome non-ATPase regulatory subunit 11; 26S proteasome regulatory subunit p44.5; 26S proteasome regulatory subunit S9; PSD11;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total PSMD11 protein.
  • Applications：  
  • WB
  • Background：  
  • Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, PSMD11 is required for proteasome assembly. Plays a key role in increased proteasome activity in embryonic stem cells (ESCs): its high expression in ESCs promotes enhanced assembly of the 26S proteasome, followed by higher proteasome activity.

    Hoffman L., FEBS Lett. 404:179-184(1997).
    Saito A., Gene 203:241-250(1997).
    The MGC Project Team; Genome Res. 14:2121-2127(2004).



 
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