Product Datasheet  
KCNMB2 Antibody  
Catalog Number: 34514  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q9Y691
    NCBI Gene ID: 10242
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human KCNMB2.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • BK channel beta-2; BKbeta2; calcium-activated potassium channel beta-2; calcium-activated potassium channel; subfamily M beta-2
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total KCNMB2 protein.
  • Applications：  
  • WB
  • Background：  
  • Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons.

    Wallner M., Proc. Natl. Acad. Sci. U.S.A. 96:4137-4142(1999).
    Brenner R., J. Biol. Chem. 275:6453-6461(2000).
    The MGC Project Team; Genome Res. 14:2121-2127(2004).



 
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