Product Datasheet
ADH7 Antibody
Catalog Number: 34396
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P40394
NCBI Gene ID: 131
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human ADH7.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- ADH-4; alcohol dehydrogenase class 4 mu/sigma; alcohol dehydrogenase class IV mu/sigma; EC 1.1.1.1; gastric alcohol dehydrogenase
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total ADH7 protein.
- Background:
- Could function in retinol oxidation for the synthesis of retinoic acid, a hormone important for cellular differentiation. Medium-chain (octanol) and aromatic (m-nitrobenzaldehyde) compounds are the best substrates. Ethanol is not a good substrate but at the high ethanol concentrations reached in the digestive tract, it plays a role in the ethanol oxidation and contributes to the first pass ethanol metabolism.
Satre M.A., J. Biol. Chem. 269:15606-15612(1994).
Zgombic-Knight M., J. Biol. Chem. 270:4305-4311(1995).
Farres J., Eur. J. Biochem. 224:549-557(1994).
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