Product Datasheet  
GRAH Antibody  
Catalog Number: 34271  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P20718
    NCBI Gene ID: 2999
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human GRAH.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

    Immunofluorescence: 1:100~1:500
  • other_names：  
  • Granzyme H [Precursor]; EC 3.4.21.-; Cytotoxic T-lymphocyte proteinase; Cathepsin G-like 2; CTSGL2
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total GRAH protein.
  • Applications：  
  • WB IF
  • Background：  
  • Cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites. Probably necessary for target cell lysis in cell-mediated immune responses. Participates in the antiviral response via direct cleavage of several proteins essential for viral replication.

    Meier M., Biochemistry 29:4042-4049(1990).
    Haddad P., Int. Immunol. 3:57-66(1991).
    Klein J.L., Tissue Antigens 35:220-228(1990).



 
© Signalway Biotechnology All Rights Reserved.