Product Datasheet
GBP1 Antibody
Catalog Number: 34250
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P32455
NCBI Gene ID: 2633
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human GBP1.
- appl_detail:
- Western blotting: 1:500~1:3000
Immunofluorescence: 1:100~1:500
- other_names:
- GBP-1; Guanine nucleotide-binding protein 1; Interferon-gamma inducible protein MAG-1; Interferon-induced guanylate-binding protein 1; MAG-1
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total GBP1 protein.
- Background:
- Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.
Cheng Y.-S.E., Mol. Cell. Biol. 11:4717-4725(1991).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
Nantais D.E., J. Leukoc. Biol. 60:423-431(1996).
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