Product Datasheet  
Cytochrome P450 2A6 Antibody  
Catalog Number: 34232  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P11509
    NCBI Gene ID: 1548
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from N-terminal of human Cytochrome P450 2A6.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • Cytochrome P450 2A6; EC 1.14.14.1; CYPIIA6; Coumarin 7-hydroxylase; P450 IIA3
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total Cytochrome P450 2A6 protein.
  • Applications：  
  • WB
  • Background：  
  • Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4-cineole 2-exo-monooxygenase. Possesses low phenacetin O-deethylation activity.

    Miles J.S., ic Acids Res. 17:2907-2917(1989).
    Yamano S., Biochemistry 29:1322-1329(1990).
    Saito S., J. Hum. Genet. 48:249-270(2003).



 
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