Product Datasheet
Collagen XIV α1 Antibody
Catalog Number: 34214
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q05707
NCBI Gene ID: 7373
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human Collagen XIV α1.
- appl_detail:
Western blotting: 1:500-1:1000
Immunofluorescence: 1:100-1:200
Immunohistochemistry: 1:50-1:100
- other_names:
- Collagen alpha-1(XIV) chain; Undulin; COEA1;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total Collagen XIV α1 protein.
- Background:
Plays an adhesive role by integrating collagen bundles. It is probably associated with the surface of interstitial collagen fibrils via COL1. The COL2 domain may then serve as a rigid arm which sticks out from the fibril and protrudes the large N-terminal globular domain into the extracellular space, where it might interact with other matrix molecules or cell surface receptors By similarity.
Nusbaum C., Nature 439:331-335(2006).
Bauer M., Biochim. Biophys. Acta 1354:183-188(1997).
Just M., J. Biol. Chem. 266:17326-17332(1991).
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