Product Datasheet
CDCA7 Antibody
Catalog Number: 34194
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9BWT1
NCBI Gene ID: 83879
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human CDCA7.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Cell division cycle-associated protein 7; Protein JPO1; JPO1;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total CDCA7 protein.
- Background:
- Participates in MYC-mediated cell transformation and apoptosis; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator.
Prescott J.E.,J. Biol. Chem. 276:48276-48284(2001).
Ota T.,Nat. Genet. 36:40-45(2004).
Hillier L.W., Nature 434:724-731(2005).
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