Product Datasheet
5-HT-6 Antibody
Catalog Number: 34155
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P50406
NCBI Gene ID: 3362
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human 5-HT-6.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- 5-HT6; 5HT6R; HTR6;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total 5-HT-6 protein.
- Background:
- This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs.
Kohen R., J. Neurochem. 66:47-56(1996).
Kopatz S.A., Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
Gregory S.G., Nature 441:315-321(2006).
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