Product Datasheet
14-3-3 ζ Antibody
Catalog Number: 34149
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P63104
NCBI Gene ID: 7534
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human 14-3-3 ζ.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- 14-3-3 protein zeta/delta; 1433Z; 143Z; FAS; Factor activating exoenzyme S
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total 14-3-3 ζ protein.
- Background:
- Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
Zupan L.A., J. Biol. Chem. 267:8707-8710(1992).
Seluja G.A., Biochim. Biophys. Acta 1395:281-287(1998).
Gevaert K., Nat. Biotechnol. 21:566-569(2003).
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