Product Datasheet
ATF5 Antibody
Catalog Number: 34127
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9Y2D1
NCBI Gene ID: 22809
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human ATF5.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Cyclic AMP-dependent transcription factor ATF-5; Activating transcription factor 5; Transcription factor ATFx; ATF5; ATFX
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total ATF5 protein.
- Background:
- Transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4.
White J.H., Proc. Natl. Acad. Sci. U.S.A. 97:13967-13972(2000).
Yamada S., Oncogene 23:5901-5911(2004).
Liu W., Biochem. Biophys. Res. Commun. 321:954-960(2004).
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