Product Datasheet
PKCB1 Antibody
Catalog Number: 34116
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9ULU4
NCBI Gene ID: 23613
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human PKCB1.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- CTCL tumor antigen se14-3; Cutaneous T-cell lymphoma associated antigen se14-3; KIAA1125; PKCB; PKCB1
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total PKCB1 protein.
- Background:
- The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated protein kinase C beta I. In addition, this protein is a cutaneous T-cell lymphoma-associated antigen. Finally, the protein contains a bromodomain and two zinc fingers, and is thought to be a transcriptional regulator. Multiple transcript variants encoding several different isoforms have been found for this gene.
Fossey S.C., Mamm. Genome 11:919-925(2000).
Eichmueller S., Proc. Natl. Acad. Sci. U.S.A. 98:629-634(2001).
Deloukas P., Nature 414:865-871(2001).
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