Product Datasheet
PEG3 Antibody
Catalog Number: 34056
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9GZU2
NCBI Gene ID: 5178
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human PEG3.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Paternally-expressed gene 3 protein; Zinc finger and SCAN domain-containing protein 24; PEG3; KIAA0287; ZSCAN24
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total PEG3 protein.
- Background:
- Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B By similarity. Possesses a tumor suppressing activity in glioma cells.
Van den Veyver I.B., J. Soc. Gynecol. Invest. 8:305-313(2001).
Kohda T., Genes Cells 6:237-247(2001).
Hiby S.E., Hum. Mol. Genet. 10:1093-1100(2001).
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