Product Datasheet
RIN3 Antibody
Catalog Number: 33985
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q8TB24
NCBI Gene ID: 79890
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human RIN3.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Ras and Rab interactor 3; Ras interaction/interference protein 3; RIN3;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total RIN3 protein.
- Background:
- Ras effector protein that functions as a guanine nucleotide exchange (GEF) for RAB5B and RAB31, by exchanging bound GDP for free GTP. Required for normal RAB31 function.
Heilig R., Nature 421:601-607(2003).
Ota T., Nat. Genet. 36:40-45(2004).
Saito K., J. Biol. Chem. 277:3412-3418(2002).
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