Product Datasheet
SPIC Antibody
Catalog Number: 33968
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q8N5J4
NCBI Gene ID: 121599
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human SPIC.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Transcription factor Spi-C; SPIC;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total SPIC protein.
- Background:
- Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression By similarity.
Carlsson R., Gene 299:271-278(2002).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
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