Product Datasheet
DCLK2 Antibody
Catalog Number: 33967
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q8N568
NCBI Gene ID: 166614
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human DCLK2.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Serine/threonine-protein kinase DCLK2; EC 2.7.11.1; Doublecortin-like and CAM kinase-like 2; Doublecortin-like kinase 2; DCLK2
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total DCLK2 protein.
- Background:
- Protein kinase with a significantly reduced C(a2+)/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm By similarity.
Totoki Y., Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Hillier L.W., Nature 434:724-731(2005).
The German cDNA consortium, Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
© Signalway Biotechnology All Rights Reserved.