Product Datasheet  
TP53INP2 Antibody  
Catalog Number: 33963  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q8IXH6 geneID 9606
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human TP53INP2.
  • reactivity：  
  • Hu Ms
  • appl_detail：  


  • Immunohistochemistry: 1:50~1:100
    Immunofluorescence: 1:100~1:500

  • other_names：  
  • p53-inducible protein U; PIG-U; PINH; T53I2; tumor protein p53 inducible nuclear protein 2
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total TP53INP2 protein.
  • Applications：  
  • IHC IF
  • Background：  

  • Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA.

    Baumgartner B.G., Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.
    Deloukas P., Nature 414:865-871(2001).
    The MGC Project Team, Genome Res. 14:2121-2127(2004).




 
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