Product Datasheet  
CDKL3 Antibody  
Catalog Number: 33959  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q8IVW4
    NCBI Gene ID: 51265
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human CDKL3.
  • reactivity：  
  • Hu
  • appl_detail：  

  • Immunohistochemistry: 1:50~1:100
  • other_names：  
  • Cyclin-dependent kinase-like 3; EC 2.7.11.22; Serine/threonine protein kinase NKIAMRE; CDKL3; NKIAMRE
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total CDKL3 protein.
  • Applications：  
  • IHC
  • Background：  
  • The protein encoded by this gene is a member of cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This gene was identified as a gene absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Midmer M., Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.
    The MGC Project Team, Genome Res. 14:2121-2127(2004).
    Greenman C., Nature 446:153-158(2007).



 
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