Product Datasheet
STEAP4 Antibody
Catalog Number: 33933
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q687X5
NCBI Gene ID: 79689
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human STEAP4.
- appl_detail:
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500
- other_names:
- EC 1.16.1.-; Six-transmembrane epithelial antigen of prostate 4; SixTransMembrane protein of prostate 2; Tumor necrosis factor; alpha-induced protein 9
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total STEAP4 protein.
- Background:
- Metalloreductase that has the ability to reduce both Fe3+ to Fe2+ and Cu2+ to Cu1+. Uses NAD+ as acceptor. Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses By similarity. Associated with obesity and insulin-resistance. Involved in inflammatory arthritis, through the regulation of inflammatory cytokines. Inhibits anchorage-independent cell proliferation.
Korkmaz C.G., Oncogene 24:4934-4945(2005).
Ota T., Nat. Genet. 36:40-45(2004).
Ohgami R.S., Nat. Genet. 37:1264-1269(2005).
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