Product Datasheet
MAP3KL4 Antibody
Catalog Number: 33930
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q5TCX8
NCBI Gene ID: 84451
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human MAP3KL4.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Mitogen-activated protein kinase kinase kinase; EC 2.7.11.25; Mixed lineage kinase 4; MLK4; KIAA1804
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total MAP3KL4 protein.
- Background:
- Negative regulator of TLR4 signaling. Does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways.
Kvasha S., Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases.
Nagase T., DNA Res. 8:85-95(2001).
Gregory S.G., Nature 441:315-321(2006).
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