Product Datasheet
PSMD2 Antibody
Catalog Number: 33890
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q13200
NCBI Gene ID: 5708
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from N-terminal of human PSMD2.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- 26S proteasome non-ATPase regulatory subunit 2; 26S proteasome regulatory subunit RPN1; 26S proteasome regulatory subunit S2; 26S proteasome subunit p97; Tumor necrosis factor type 1 receptor-associated protein 2
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total PSMD2 protein.
- Background:
- Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1.
Tsurumi C., Eur. J. Biochem. 239:912-921(1996).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Dunbar J.D., J. Immunol. 158:4252-4259(1997).
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