Product Datasheet  
TF2H2 Antibody  
Catalog Number: 33874  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q13888
    NCBI Gene ID: 2966
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from N-terminal of human TF2H2.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • TFIIH basal transcription factor complex p44 subunit; Basic transcription factor 2 44 kDa subunit; BTF2-p44; General transcription factor IIH polypeptide 2; GTF2H2
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total TF2H2 protein.
  • Applications：  
  • WB
  • Background：  
  • Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. The N-terminus interacts with and regulates XPD whereas an intact C-terminus is required for a successful escape of RNAP II form the promoter.

    Humbert S., EMBO J. 13:2393-2398(1994).
    The MGC Project Team, Genome Res. 14:2121-2127(2004).
    van der Steege G., Eur. J. Hum. Genet. 3:87-95(1995).



 
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