Product Datasheet
TNFC Antibody
Catalog Number: 33861
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q06643
NCBI Gene ID: 4050
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from C-terminal of human TNFC.
- appl_detail:
- Western blotting: 1:500~1:3000
Immunofluorescence: 1:100~1:500
- other_names:
- Lymphotoxin-beta; LT-beta; Tumor necrosis factor C; TNF-C; Tumor necrosis factor ligand superfamily member 3
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total TNFC protein.
- Background:
- Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface. Isoform 2 is probably non-functional.
Browning J.L., Cell 72:847-856(1993).
Warzocha K., Biochem. Biophys. Res. Commun. 238:273-276(1997).
Neville M.J., J. Immunol. 162:4745-4754(1999).
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