Product Datasheet
TLE4 Antibody
Catalog Number: 33856
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q04727
NCBI Gene ID: 7091
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human TLE4.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Transducin-like enhancer protein 4; TLE4; KIAA1261;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total TLE4 protein.
- Background:
- Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES By similarity.
Nagase T., DNA Res. 6:337-345(1999).
Humphray S.J., Nature 429:369-374(2004).
Stifani S., Nat. Genet. 2:119-127(1992).
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