Product Datasheet
MEF2B Antibody
Catalog Number: 33845
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q02080
NCBI Gene ID: 4207
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human MEF2B.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- MDS1-EVI1; PRDM3; myelodysplasia syndrome 1; myelodysplasia syndrome-associated 1;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total MEF2B protein.
- Background:
- Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription.
Yu Y.-T., Genes Dev. 6:1783-1798(1992).
Pollock R., Genes Dev. 5:2327-2341(1991).
Grimwood J., Nature 428:529-535(2004).
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