Product Datasheet  
AF4 Antibody  
Catalog Number: 33800  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P51825
    NCBI Gene ID: 4299
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from N-terminal of human AF4.
  • reactivity：  
  • Hu
  • appl_detail：  

  • Immunohistochemistry: 1:50~1:100
  • other_names：  
  • AF4; AFF1; FEL protein; MLLT2; Proto-oncogene AF4
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total AF4 protein.
  • Applications：  
  • IHC
  • Background：  
  • A chromosomal aberration involving AFF1 is associated with acute leukemias. Translocation t(4;11)(q21;q23) with MLL/HRX. The result is a rogue activator protein. Belongs to the AF4 family.?

    Nakamura T., Proc. Natl. Acad. Sci. U.S.A. 90:4631-4635(1993).
    Morrissey J., Blood 81:1124-1131(1993).
    Gu Y., Cell 71:701-708(1992).



 
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