Product Datasheet
STAT5A Antibody
Catalog Number: 33769
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P42229
NCBI Gene ID: 6776
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human STAT5A.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- MGF; MPF; Mammary gland factor; STA5A; STAT5
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total STAT5A protein.
- Background:
- Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.
Hou J., Immunity 2:321-329(1995).
Litterst C.M., J. Biol. Chem. 278:45340-45351(2003).
Martens N., J. Biol. Chem. 280:13817-13823(2005).
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