Product Datasheet
TF2E2 Antibody
Catalog Number: 33739
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P29084
NCBI Gene ID: 2961
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human TF2E2.
- appl_detail:
- Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
- other_names:
- GTF2E2; T2EB; TF2E2; Transcription initiation factor IIE beta subunit;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total TF2E2 protein.
- Background:
- Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
Peterson M.G., Nature 354:369-373(1991).
Sumimoto H., Nature 354:401-404(1991).
Kang S.-W., Genes Cells 5:251-263(2000).
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