Product Datasheet
LGALS1 Antibody
Catalog Number: 34281
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P09382
NCBI Gene ID: 3956
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from Internal of human LGALS1.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- 14 kDa laminin-binding protein; 14 kDa lectin; Beta-galactoside-binding lectin L-14-I; DKFZp686E23103; Gal-1
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total LGALS1 protein.
- Background:
- May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.
Hirabayashi J., Biochim. Biophys. Acta 1008:85-91(1989).
Couraud P.-O., J. Biol. Chem. 264:1310-1316(1989).
Abbott W.M., Biochem. J. 259:291-294(1989).
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