Product Datasheet
CREM Antibody
Catalog Number: 33850
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q03060
NCBI Gene ID: 1390
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human CREM.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- CREM-alpha; cAMP-responsive element modulator; cAMP-responsive element modulator; alpha isoform CREM; CREM-beta
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total CREM protein.
- Background:
- Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Plays a role in spermatogenesis and is involved in spermatid maturation By similarity.
Masquilier D., Cell Growth Differ. 4:931-937(1993).
Meyer T.E., Nucleic Acids Res. 20:6106-6106(1992).
Fujimoto T., J. Biochem. 115:298-303(1994).
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