Product Datasheet  
Adrenergic Receptor alpha-2B Antibody  
Catalog Number: 33700  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P18089
    NCBI Gene ID: 151
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human Adrenergic Receptor alpha-2B.
  • reactivity：  
  • Hu
  • appl_detail：  


  • Immunofluorescence: 1:100~1:500
  • other_names：  
  • ADA2B; ADRA2L1; ADRA2RL1; ADRARL1; ALPHA2BAR
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total Adrenergic Receptor alpha-2B protein.
  • Applications：  
  • IF
  • Background：  
  • Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol.

    Lomasney J.W., Proc. Natl. Acad. Sci. U.S.A. 87:5094-5098(1990).
    Weinshank R.L., Mol. Pharmacol. 38:681-688(1990).
    Small K.M., J. Biol. Chem. 276:4917-4922(2001).



 
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