Product Datasheet
ZNF24 Antibody
Catalog Number: 33691
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P17028
NCBI Gene ID: 7572
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from N-terminal of human ZNF24.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Zinc finger protein 18; Zinc finger protein KOX11; Heart development-specific gene 1 protein; Zinc finger protein with KRAB and SCAN domains 6; ZNF18
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total ZNF24 protein.
- Background:
- Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5'-TCAT-3' DNA sequence By similarity. Has transcription repressor activity in vitro.
Guo L.L., Yi Chuan 27:523-530(2005).
Ota T., Nat. Genet. 36:40-45(2004).
Thiesen H.-J., New Biol. 2:363-374(1990).
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