Product Datasheet
HMG17 Antibody
Catalog Number: 33651
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P05204
NCBI Gene ID: 3151
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human HMG17.
- appl_detail:
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500
- other_names:
- HMG17; high mobility group protein N2; high-mobility group (nonhistone chromosomal) protein 17; high-mobility group nucleosomal binding domain 2; high-mobility group nucleosome binding domain 2
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total HMG17 protein.
- Background:
- Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation By similarity.
Landsman D., J. Biol. Chem. 261:7479-7484(1986).
Gregory S.G., Nature 441:315-321(2006).
Giancotti V., Eur. J. Biochem. 198:211-216(1991).
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