Product Datasheet
BCKD Antibody
Catalog Number: 33570
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: O14874
NCBI Gene ID: 10295
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from Internal of human BCKD.
- appl_detail:
- Western blotting: 1:500~1:3000
Immunofluorescence: 1:100~1:500
- other_names:
- [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase; mitochondrial [Precursor]; EC 2.7.11.4; Branched-chain alpha-ketoacid dehydrogenase kinase; BCKDHKIN
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total BCKD protein.
- Background:
- Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex By similarity.
Chuang J.C., Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases.
The MGC Project Team, Genome Res. 14:2121-2127(2004).
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