Product Datasheet
CDC7 Antibody
Catalog Number: 33558
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: O00311
NCBI Gene ID: 8317
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human CDC7.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Cell division cycle 7-related protein kinase; EC 2.7.11.1; CDC7-related kinase; HsCdc7; huCdc7
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total CDC7 protein.
- Background:
- Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3.
Sato N., EMBO J. 16:4340-4351(1997).
Hess G.F., Gene 211:133-140(1998).
Jiang W., Proc. Natl. Acad. Sci. U.S.A. 94:14320-14325(1997).
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